KIN1400 is an innate immune agonist of IRF3 activation to mediate broad-spectrum antiviral activity. KIN1400 is a RLR pathway agonist.
Keywords: KIN1400 | Supplier | IRF3 agonist | KIN 1400 | KIN-1400 | CAS [446826-86-4] | RLR pathway | RLR | agonist | Receptors | Innate immunity | Antiviral | RLR | Transcription factor interferon regulatory factor 3 | RIG-I-like receptor pathway
| CAS Number | 446826-86-4 |
| Molecular Formula | C24H17F2N3O2S |
| Purity | ≥95% |
| IUPAC Name | 7-[(1,3-benzothiazol-2-ylamino)-[4-(difluoromethoxy)phenyl]methyl]quinolin-8-ol |
| InChI | InChI=1S/C24H17F2N3O2S/c25-23(26)31-16-10-7-15(8-11-16)20(29-24-28-18-5-1-2-6-19(18)32-24)17-12-9-14-4-3-13-27-21(14)22(17)30/h1-13,20,23,30H,(H,28,29) |
| SMILES | C1=CC=C2C(=C1)N=C(S2)NC(C3=CC=C(C=C3)OC(F)F)C4=C(C5=C(C=CC=N5)C=C4)O |
| Reference | S Pattabhi et al. Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway. J Virol. 2015 Dec 16;90(5):2372-87. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
